How stem cells could fix type 1 diabetes
نویسندگان
چکیده
Trials to replace the pancreatic ? cells that are destroyed by this autoimmune disease raising hopes of a cure.
منابع مشابه
Stem cells therapy for type 1 diabetes.
In this article, we have reviewed the developments of studies of stem cells therapy for type 1 diabetes since this century. Review of the literature was based on computer searches (PubMed) and our studies. Type 1 diabetes can now be ameliorated by islet transplantation, but this treatment is restricted by the scarcity of islet tissue. Hopes for a limitless supply of a substitute for primary isl...
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background : type 1 diabetes mellitus (t1dm) is an autoimmune disease characterized by selective destruction of pancreatic beta cells. methods: the study included 80 children, 20 of them have t1dm, 40 children were selected from first degree relatives to the same child and 20 healthy children serve as control. body mass index (bmi) was calculated, random blood glucose and glycosylated hemoglo...
متن کاملStem cell treatment for type 1 diabetes
Type 1 diabetes mellitus (T1DM) is a common chronic disease in children, characterized by a loss of β cells, which results in defects in insulin secretion and hyperglycemia. Chronic hyperglycemia causes diabetic complications, including diabetic nephropathy, neuropathy, and retinopathy. Curative therapies mainly include diet and insulin administration. Although hyperglycemia can be improved by ...
متن کاملHow Does Type 1 Diabetes Develop?
Despite decades of acknowledging that a loss of insulin-producing pancreatic b-cells is central to the disorder now referred to as type 1 diabetes, the specific roles for genetic susceptibility, environmental factors, the immune system, and b-cells themselves in the pathogenic processes underlying the disorder remain unclear (1,2). Looking back over this period, one can identify a handful of co...
متن کاملMesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes.
Mesenchymal stem cells (MSCs) are multipotent non-haematopoietic progenitor cells that are being explored as a promising new treatment for tissue regeneration. Although their immunomodulatory properties are not yet completely understood, their low immunogenic potential together with their effects on immune response make them a promising therapeutic tool for severe refractory autoimmune diseases...
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ژورنال
عنوان ژورنال: Nature
سال: 2021
ISSN: ['1476-4687', '0028-0836']
DOI: https://doi.org/10.1038/d41586-021-01842-x